Substrate: Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)
Seq-ID: P14598 [Homo sapiens]
Download:fasta csv
Interaction Network(s): STRING   NetworKIN  
External Source(s): Phosida
MINT Interaction(s):
[show]
MINT-58638   TF65_HUMAN
MINT-66383   TRIM9_HUMAN
MINT-74863   ACTB_HUMAN
MINT-3973484   KPCA_HUMAN
MINT-3973536   KPCD_HUMAN
MINT-7135171   GNAI2_HUMAN
MINT-7300360   NCF4_HUMAN
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
SH3 domain binding,
phosphoinositide binding,
GTPase activity,
GTP binding,
electron carrier activity		 cytosol,
NADPH oxidase complex,
soluble fraction		 protein targeting to membrane,
superoxide anion generation,
cellular defense response,
innate immune response,
cell communication,
respiratory burst
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 208 MKAKRGWIPASFLEPLDSPDE CK2_group 11485312
LTP
0.88
 MOD_CK2_1
 - SH3
0.43
 1NG2 2.46%
S 283 GYFPSMYLQKSGQDVSQAQRQ CK2_group 11485312
LTP
0.78
 - SH3
0.51
 1NG2 53.28%
S 303 QIKRGAPPRRSSIRNAHSIHQ PKC_alpha 8626435
LTP
1.00
 MOD_PKA_1
 - -
0.76
 1NG2 44.26%
S 303 QIKRGAPPRRSSIRNAHSIHQ PKA_group 7520867
LTP
1.00
 MOD_PKA_1
 - -
0.76
 1NG2 44.26%
S 303 QIKRGAPPRRSSIRNAHSIHQ PKC_alpha 7520867
LTP
1.00
 MOD_PKA_1
 - -
0.76
 1NG2 44.26%
S 304 IKRGAPPRRSSIRNAHSIHQR PKB_group 8626435
LTP
0.09
 - -
0.77
 1NG2 57.38%
S 304 IKRGAPPRRSSIRNAHSIHQR PKC_alpha 8626435
LTP
0.09
 - -
0.77
 1NG2 57.38%
S 304 IKRGAPPRRSSIRNAHSIHQR PKB_group 7520867
LTP
0.09
 - -
0.77
 1NG2 57.38%
S 304 IKRGAPPRRSSIRNAHSIHQR PKC_alpha 7520867
LTP
0.09
 - -
0.77
 1NG2 57.38%
S 304 IKRGAPPRRSSIRNAHSIHQR PKB_group 12734380
LTP
0.09
 - -
0.77
 1NG2 57.38%
S 315 IRNAHSIHQRSRKRLSQDAYR PKC_alpha 8626435
LTP
0.77
 - -
0.66
 1NG2 86.89%
S 320 SIHQRSRKRLSQDAYRRNSVR PKA_group 8626435
LTP
1.00
 MOD_PKA_1
 - -
0.59
 1NG2 58.20%
S 320 SIHQRSRKRLSQDAYRRNSVR PKC_alpha 8626435
LTP
1.00
 MOD_PKA_1
 - -
0.59
 1NG2 58.20%
S 320 SIHQRSRKRLSQDAYRRNSVR PKA_group 7520867
LTP
1.00
 MOD_PKA_1
 - -
0.59
 1NG2 58.20%
S 320 SIHQRSRKRLSQDAYRRNSVR PKC_alpha 7520867
LTP
1.00
 MOD_PKA_1
 - -
0.59
 1NG2 58.20%
S 328 RLSQDAYRRNSVRFLQQRRRQ PKA_group 8626435
LTP
0.99
 MOD_PKA_1
 - -
0.56
 1NG2 0.00%
S 328 RLSQDAYRRNSVRFLQQRRRQ PKC_alpha 8626435
LTP
0.99
 MOD_PKA_1
 - -
0.56
 1NG2 0.00%
S 328 RLSQDAYRRNSVRFLQQRRRQ PKB_group 7520867
LTP
0.99
 MOD_PKA_1
 - -
0.56
 1NG2 0.00%
S 328 RLSQDAYRRNSVRFLQQRRRQ PKC_alpha 7520867
LTP
0.99
 MOD_PKA_1
 - -
0.56
 1NG2 0.00%
S 328 RLSQDAYRRNSVRFLQQRRRQ PKB_group 12734380
LTP
0.99
 MOD_PKA_1
 - -
0.56
 1NG2 0.00%
S 345 RRRQARPGPQSPGSPLEEERQ - 8626435
LTP
0.37
 MOD_ProDKin_1
 - p47_phox_C
0.92
 --
S 345 RRRQARPGPQSPGSPLEEERQ MAPK14 15629715
LTP
0.37
 MOD_ProDKin_1
 - p47_phox_C
0.92
 --
S 345 RRRQARPGPQSPGSPLEEERQ MAPK3 15629715
LTP
0.37
 MOD_ProDKin_1
 - p47_phox_C
0.92
 --
S 345 RRRQARPGPQSPGSPLEEERQ - 7520867
LTP
0.37
 MOD_ProDKin_1
 - p47_phox_C
0.92
 --
S 348 QARPGPQSPGSPLEEERQTQR CK2_group 11485312
LTP
0.81
 MOD_CK2_1
 - p47_phox_C
0.94
 --
S 348 QARPGPQSPGSPLEEERQTQR PKA_group 8626435
LTP
0.81
 MOD_CK2_1
 - p47_phox_C
0.94
 --
S 348 QARPGPQSPGSPLEEERQTQR PKC_alpha 8626435
LTP
0.81
 MOD_CK2_1
 - p47_phox_C
0.94
 --
S 348 QARPGPQSPGSPLEEERQTQR MAPK14 15629715
LTP
0.81
 MOD_CK2_1
 - p47_phox_C
0.94
 --
S 348 QARPGPQSPGSPLEEERQTQR MAPK3 15629715
LTP
0.81
 MOD_CK2_1
 - p47_phox_C
0.94
 --
S 359 PLEEERQTQRSKPQPAVPPRP PKA_group 8626435
LTP
0.71
 MOD_PKA_2
 - p47_phox_C
0.94
 --
S 359 PLEEERQTQRSKPQPAVPPRP PKC_alpha 8626435
LTP
0.71
 MOD_PKA_2
 - p47_phox_C
0.94
 --
S 359 PLEEERQTQRSKPQPAVPPRP - 9857051
LTP
0.71
 MOD_PKA_2
 - p47_phox_C
0.94
 --
S 370 KPQPAVPPRPSADLILNRCSE PKA_group 8626435
LTP
1.00
 MOD_PKA_2
 - p47_phox_C
0.80
 --
S 370 KPQPAVPPRPSADLILNRCSE PKC_alpha 8626435
LTP
1.00
 MOD_PKA_2
 - p47_phox_C
0.80
 --
S 370 KPQPAVPPRPSADLILNRCSE - 9857051
LTP
1.00
 MOD_PKA_2
 - p47_phox_C
0.80
 --
S 379 PSADLILNRCSESTKRKLASA - 7520867
LTP
0.80
 - p47_phox_C
0.64
 --

Substrate: Neutrophil cytosol factor 1 (Neutrophil cytosol factor 1)
Seq-ID: Q09014 [Mus musculus]
Download:fasta csv
Interaction Network(s):
External Source(s): PhosidaPhosida
MINT Interaction(s):
MINT-19593   ABI1_MOUSE
GO-Terms:
[show]
Molecular FunctionCellular ComponentBiological Process
phosphoinositide binding,
superoxide-generating NADPH oxidase activity,
protein binding		 cytosol hydrogen peroxide biosynthetic process,
response to yeast,
protein targeting to membrane,
neutrophil mediated killing of gram-positive bacterium,
superoxide anion generation,
cellular defense response,
inflammatory response,
respiratory burst involved in defense response,
leukotriene metabolic process,
neutrophil mediated killing of fungus,
cell communication,
cell proliferation,
negative regulation of smooth muscle contraction
Conservation:
Click on table headers for sorting
Res. Pos. Sequence Kinase PMID Src Cons. ELM Binding Domain SMART/Pfam IUPRED score PDB P3D Acc.
S 321 SIHQRSRKRLSQDTYRRNSVR - 19144319
HTP
1.00
 - -
0.62
 - low

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